Rho dependent Termination
● This type of termination occur in Prokaryotes for termination of transcription.
◇ Transcription = Synthesis of RNA from DNA.
● Dna which have such a termination sequence which terminates the transcription only in presence of rho factor are called rho dependent termination.
● This termination sequence is rich in C but devoid of G .This types of sequence is necessary for function rho protein .
● Rho protein binds with mRNA which is elongated by rna polymerase at rut site (rho utilization site) and then rho protein moves from 5' to 3' end .
● When RNA polymerase reaches rho dependent termination sequence then rho protein shows its helicase activity and unwind DNA-RNA hybrid.
● This will disrupt and terminate transcription bubble and new synthesized mRNA is released.
(Helicase is a enzyme that can unwind the dna strand or we can say breaks H bonds present in between the double helix of DNA )
◇ Transcription = Synthesis of RNA from DNA.
● Dna which have such a termination sequence which terminates the transcription only in presence of rho factor are called rho dependent termination.
● This termination sequence is rich in C but devoid of G .This types of sequence is necessary for function rho protein .
● Rho protein binds with mRNA which is elongated by rna polymerase at rut site (rho utilization site) and then rho protein moves from 5' to 3' end .
● When RNA polymerase reaches rho dependent termination sequence then rho protein shows its helicase activity and unwind DNA-RNA hybrid.
● This will disrupt and terminate transcription bubble and new synthesized mRNA is released.
(Helicase is a enzyme that can unwind the dna strand or we can say breaks H bonds present in between the double helix of DNA )
Comments